Yes, the Canon EOS R3 works with the DJI RS 4 Mini — with conditions (see below).
Canon EOS R3 body weighs approximately 1015g (with battery and memory card, including the integrated vertical grip, per Canon specifications). Paired with a Canon RF 24-105mm f/4 L IS USM lens (approximately 700g) -- a versatile full-frame zoom for professional work -- combined weight is approximately 1715g. This falls within DJI RS 4 Mini's stated 2kg (4.4lbs) payload capacity per DJI's own product page, though with limited margin for heavier lenses.
Conditions for compatibility
Verdict assumes a Canon RF 24-105mm f/4 L IS USM lens (approximately 700g, per Canon lens specifications). EOS R3 body (~1015g, with battery and memory card) + this lens = approximately 1715g total -- only 285g under the RS 4 Mini's 2kg limit. Any RF telephoto lens heavier than approximately 985g will exceed the payload limit. Verify your specific lens weight carefully before pairing with this gimbal.
“Canon RF 24-105mm F4L IS USM lens weight approx. 700g (per Canon's published lens specifications).”
“Body (including battery and CFexpress card) Based on CIPA guidelines. Approx. 1015 g Approx. 35.80 oz.”
“2kg/4.4lbs Payload for Camera and Phone It supports a wide range of mainstream mirrorless cameras and lens combinations, lightweight vlog cams,”
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Compatibility inferred from spec rule (citations above are manufacturer-verified)