No, the Focusrite Scarlett 2i2 (4th Gen) is not compatible with the HyperX QuadCast 2 S.
HyperX QuadCast 2 S is a USB-C condenser microphone that connects to a computer via USB-C. Scarlett 2i2's only mic inputs are 2 combo XLR/TRS preamp inputs -- its own USB-C port is a host connection, not a USB mic input. USB microphones cannot be routed through Scarlett 2i2's signal chain.
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