Yes, the Canon EOS R50 works with the Lexar Professional 2000x 128GB SD UHS-II — with conditions (see below).
Canon EOS R50's SD slot is UHS-I only. Canon's own R50 manual states UHS-II cards operate in backward-compatible UHS-I mode in this slot -- that's the U3/UHS-I floor, not the V60/V90 UHS-II rating. Lexar Professional 2000x 128GB SD UHS-II is rated V90, a UHS-II-only guarantee that does not survive that fallback -- no UHS-I-mode or U-class figure is sourced for this card, so real sustained write speed here is unconfirmed. Verify before relying on it for 4K30.
Conditions for compatibility
Falls back to UHS-I mode on Canon EOS R50's SD slot -- Lexar Professional 2000x 128GB SD UHS-II's V90 rating requires UHS-II and does not apply here. Verify real sustained write speed in UHS-I mode before relying on it for 4K30.
“SD/SDHC/SDXC memory cards UHS-I cards supported.”
Last verified:
Compatibility inferred from spec rule (citations above are manufacturer-verified)